1. It can cause allergic reactions and irritation to the skin and mucous membranes, but it is milder than the stimulation of iodine.
2. Topical use in infants may lead to significant absorption of iodine (including absorption after use in pregnant and lactating women).
3. Local stimulation, itching, and burning sensation are common reactions, and large-scale and long-term use can occasionally lead to neutropenia.
4. Patients with severe burns may experience metabolic acidosis.
5. Patients with extensive burns have also reported liver damage.
6. Other adverse reactions include contact dermatitis, hypothyroidism, and iodine poisoning.