Polyvinylpyrrolidone (PVP) is a widely used pharmaceutical excipient with various uses in the field of pharmaceutical preparations:
1. Disintegrators and fillers: Polyvinone is often used as a disintegrant and filler for tablets, granules, pills, and hard capsules.
2. Adhesive and coating materials: It can be used as an adhesive and coating material for solid formulations.
3. Solid dispersion carrier: Polyvinone can serve as a carrier for solid dispersion.
4. Sustained release and controlled release formulations: It can serve as a co solvent or dispersion stabilizer for sustained-release and controlled release formulations.
5. Co solvent or dispersion stabilizer: Polyvinone can be used as a co solvent or dispersion stabilizer, especially in liquid formulations.
6. Additives for ophthalmic drugs: Povidone can be used in ophthalmic drugs as a detoxifier, extender, lubricant, etc.
7. Other uses: Povidone can also be used for contact lenses to increase its hydrophilicity; As a low-temperature preservative, used for the stability of enzymes and thermosensitive drugs; As a deproteinizing agent for contact lenses.
In summary, povidone, as a multifunctional excipient, has broad application value in pharmaceutical formulations.