PVP (polyvinylpyrrolidone), as a medicinal excipient, is mainly used to improve the solubility of drugs and promote drug absorption. In tablets formed by PVP, the drug rapidly dissolves in the digestive tract, causing local swelling and disintegration of the tablet, thereby accelerating the dissolution and absorption process of the drug. In addition, PVP can also serve as a co precipitant for drugs, and its mechanism of action is that the carbonyl group of PVP molecules can bind with active hydrogen atoms in insoluble drug molecules, forming hydrogen bonds. In this way, drug molecules that were originally difficult to dissolve will exist in an amorphous state in PVP macromolecules, while the high solubility of PVP is not affected, making these insoluble drug molecules easier to decompose by water. This effect not only benefits the dissolution of drugs, but also prolongs their effectiveness, such as significant effects on drugs such as penicillin, chloramphenicol, insulin, sodium salicylate, procaine, and cortisone.